Lacey Chabert

Eliza Thornberry (voice)

Jodi Carlisle

Marianne Thornberry (voice)

Tim Curry

Nigel Thornberry (voice)

Flea

Donnie Thornberry (voice)

Danielle Harris

Debbie Thornberry (voice)

Tom Kane

Darwin (voice)

Keith Szarabajka

Kip O'Donnell (voice),Kip O'Donnell / Puma (voice),Kip O'Donnell / Otter (voice)

Betty White

Sophie Hunter (voice)

Dee Bradley Baker

Kix / Macqaque Wallah (voice),Tiger / Monkey (voice),Crocodile #1 (voice),.....

Jonathan Taylor Thomas

Tyler Tucker (voice)